Active substances: Ciprofloxacin
Flank pain is nearly universal, and its absence should raise suspicion of an alternative diagnosis.
A positive urinalysis confirms the diagnosis in patients with a compatible history and physical examination. Urine culture should be obtained in all patients to guide antibiotic therapy if the patient does not respond to initial empiric antibiotic regimens.
Escherichia coli is the most common pathogen in acute pyelonephritis, and in the past decade, there has been an increasing rate of E.
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