Active substances: Gabapentin
Abstract Background Mitochondrial dysfunction due to respiratory chain impairment is a key feature in pathogenesis of Friedreich ataxia.
Friedreich ataxia affects the nervous system, heart and pancreas. The method has not been used in neurological disorders so far. Methods 16 patients all with genetically confirmed Friedreich ataxia and homozygous for the GAA expansion were recruited from the Department of Neurology, St.
All participants gave written informed consent to the study. The study was approved by the ethic committee of the Ruhr-University Bochum, registration-number 2718.
Two patients had a late onset of the disease 28 and 30 years, only one was still able to walk independently. Betoptic S Betaxololum eye drops, susp. Biafine Trolaminum emuls. Bifonazol-SL crm.
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