Active substances: Norfloxacin
Among these, tendon problems and exacerbation of the symptoms of the neurological disorder myasthenia gravis are the subject of "black box" warnings in the United States.
Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients. Simultaneous use of corticosteroids is present in almost one-third of quinolone-associated tendon rupture.
Fluoroquinoline treatment is associated with risk that is similar to or less than that associated with broad spectrum cephalosporins. Therefore, cyclosporine serum levels should be monitored and appropriate cyclosporine dosage adjustments made when these drugs are used concomitantly.
Medications Some quinolones exert an inhibitory effect on the cytochrome P-450 system, thereby reducing theophylline clearance and increasing theophylline blood levels.
Additionally other fluoroquinolones, especially enoxacin, and to a lesser extent ciprofloxacin and pefloxacin, also inhibit the metabolic clearance of theophylline. As such, these drug interactions involving the fluoroquinolones appear to be drug specific rather than a class effect.
The recommended dose is 1 film-coated tablet 400 mg norfloxacin once daily. Swallow the tablets with a glass of water at least one hour before or two hours after a meal or drink of milk. Preferably the tablets should be taken in the morning and evening.Medical uses The initial approval by chronic complicated kidney infections has been.
If you only take a single daily dose, always take this at the same time of day. The duration of treatment depends on the type and severity of infection.
For women with acute, uncomplicated inflammation of the bladder, the usual duration of treatment is a 3 day course of this medicine with the recommended dose. In the treatment of urinary tract infections, adults will generally need to use this medicine for 7-10 days.
In chronic inflammation of the prostate the usual duration of treatment is 4 weeks. The symptoms of urinary tract infection, such as a burning sensation experienced during passing water, pain, and fever, will generally disappear within 1-2 days.
However, the treatment course with this medicine should be continued for up to 12 weeks in chronic relapsing urinary tract infections. If you take more Norfloxacin 400 mg than you should If you have taken a double dose, you only need to contact your doctor if side effects occur.
Continue taking your medicine regularly as prescribed.