Active substances: Azithromycin
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Azithromycin is a semisynthetic, 15-membered lactone ring azalide related to the macrolide antibiotic class indicated for the treatment of a wide range of bacterial infections and chronic inflammatory disorders.
The broad spectrum and favorable pharmacokinetics make azithromycin routinely used for urogenital and airway infections, while current ophthalmological use is limited to topical treatment against ocular surface infections, such as bacterial conjunctivitis, trachoma, and blepharitis.
In addition to antimicrobial activity, azithromycin exerts immunomodulatory and anti-inflammatory effects that contribute to the clinical outcome amelioration in the pathologies where azithromycin is currently used and might suggest the application of the macrolide in other pathological contests where these phenomena are implicated.